The Warriors (12-2) have won eight straight and kept their starters on the bench for the entire fourth quarter after taking a 29-point lead.
Indiana (7-8) looked tired after earning its first road win Sunday night in overtime at Oklahoma City. The Pacers also played short-handed, with three-time All-Star Paul George, starting center Myles Turner and backup forward C.J. Miles all out with injuries.
Golden State took control with an early 15-4 run, pulled away with a 13-4 spurt late in the second quarter and extended its 61-42 halftime lead to 100-71 after three.
Kevin Durant had 14 points, 11 rebounds and six assists for the Warriors.
Warriors: Finished 13 of 36 on 3-pointers, with six players making at least one. … Golden State had 31 assists on 40 baskets. … The Warriors grabbed a season-high 60 rebounds. … Former Pacers forward David West drew a few boos when he made his first basket, early in the second quarter.
Pacers: Point guard Jeff Teague left in the third with a sprained right ankle and did not return. … Al Jefferson had four points and Glenn Robinson III added eight points as the replacements for Turner and George, respectively. … Indiana is 6-3 at home, where it will play its next three games.
Warriors: Return home Wednesday for the first of two straight games against the Lakers. Earlier this month, Los Angeles won the first of four meetings this season.
Pacers: Host Atlanta on Wednesday. It will be the first time Teague faces his former team since being traded to Indiana this summer.