Durant finished with 30 points and 12 rebounds to lead the Thunder, who have won five in a row.
Westbrook scored 27 points and added 12 assists but fell five rebounds shy of another triple-double. He had two straight coming in and five on the season.
The Thunder have won 20 of 24 and are the only team in the Northwest Division with a winning record. They are 12 games in front of Utah.
The Nuggets announced before the game they had signed general manager Tim Connelly and assistant general manager Arturas Karnisovas to multi-year contract extensions.