Marc Gasol and Zach Randolph added 16 points apiece, while Courtney Lee contributed 13. Conley and Gasol both connected on 7 of 11 shots and Randolph missed only one of his eight attempts as Memphis shot close to 60 percent for the game before finishing at 56 percent.
Kobe Bryant, playing in only the first and third quarters, scored 19 for the Lakers, with 14 in the opening quarter. Larry Nance Jr. had 17 points and 11 rebounds, while Jordan Clarkson scored 12 points and D'Angelo Russell finished with 10.
Memphis snapped a two-game skid, while Los Angeles lost its third straight and fifth in the last six.
Memphis outscored the Lakers in every quarter except the fourth, when the lead reached 25 before reserves closed out the game. The Grizzlies used their inside game to hold a 44-28 advantage in the paint.
Bryant scored 14 of the Lakers’ 23 first-quarter points, but Los Angeles already trailed by nine.
The Memphis lead would reach 59-46 at the break as four Grizzlies were already in double figures, led by 12 points from Gasol and 11 by Conley.
Memphis shot 56 percent for the half, while the Lakers were limited to 36 percent. Los Angeles finished the game at 38 percent.
The Grizzlies extended the lead to 22 in the third period before carrying a 92-74 advantage into the fourth. Nance had 13 in the quarter for the Lakers.
Lakers: Bryant has more points against the Grizzlies than any other player. He also holds the record for most points scored by an NBA player at the FedExForum, when he had 60 on March 22, 2007. . Nance, a rookie from Wyoming, recorded his first career double-double. . Julius Randle had 13 rebounds, marking the 26th time this season he has led Los Angeles in rebounding and the 17th game with more than 10 boards.
Grizzlies: With his first field goal, Gasol passed Shareef Abdur-Rahim (7,801 points) for 4th on the Grizzlies’ scoring list. . Memphis is 8-2 this season on the second night of a back-to-back. . Mario Chalmers scored 11 points and had seven assists.